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UCLA researchers have tapped into stem cells’ regenerative ability to form new bone. They have identified the bone-forming properties of a protein known as NELL-1. The possibilities are promising for people with osteopenia and osteoporosis, who suffer from bone loss. The use of NELL-1 may be successful in producing new bone formation in these patients at some point in the future.
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— Barbara Worthington, editor |
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Study Shows Bone-Building Protein’s Impact on Bone Stem Cells
A new study by UCLA researchers shows that administering the protein NELL-1 intravenously stimulates significant bone formation through the regenerative ability of stem cells.
These preclinical results could one day have an impact on the development of a treatment for osteoporosis, which affects more than 200 million people worldwide, as well as potentially helping those with traumatic bone injuries, such as members of the military or astronauts who lose bone density while in space.
The study, published in the journal Nature Communications, was led by cosenior authors Kang Ting, DMD, DMSc, chair of orthodontics and the division of growth and development in the UCLA School of Dentistry, and Chia Soo, MD, FACS, a professor and vice chair for research in the UCLA Division of Plastic and Reconstructive Surgery in the David Geffen School of Medicine and a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.
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Malnutrition Vigilance During Care Transitions
Physical and psychosocial changes in older adults can lead to significant reductions in oral intake. Physicians must identify diagnostic criteria that signal elders' increased risk of malnutrition, particularly during transitions of care. Read more »
Insight and Information Are Key to Implementing Palliative Care
One of the fastest growing fields in medicine, palliative care focuses on a patient's quality of life, providing treatment through all the challenges of his or her clinical course. Read more »
The MIND Diet — Fighting Dementia With Food
A recent study from Rush University has identified a dietary pattern that can significantly reduce the risk of developing Alzheimer's disease, even in patients with only moderate compliance. Read more » |
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Sizewise Immerse
Sizewise Immerse assists in preventing or treating pressure ulcers and full-thickness burns and aids in the healing of skin grafts and reconstructive flaps. Evidence-based clinical practice has shown that a deep-cell, low-air-loss mattress contributes to improved wound site healing. The company says a study using the mattresses at a hospital resulted in eliminating the use of air-fluidized therapy for postmyocutaneous flaps. Learn more »
HydroWorx
Aquatic therapy treadmill company HydroWorx recently unveiled the high-tech 300 Series water machine. The new machine is in a transparent glass case that fills with water in less than three minutes. Its smaller footprint allows aquatic therapy in several venues, including retirement communities. “This product has the potential to transform the market in several segments, including sports medicine, military, senior living, health care, and fitness,” says Anson Flake, HydroWorx CEO and cofounder. Learn more » |
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