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Editor's e-Note
Preliminary research findings suggest that modified intermittent fasting (MIF) is beneficial for individuals with psoriasis. Patients who followed a MIF 5:2 diet (a normal diet with two fasting days) experienced reduced skin scaling and thickness.

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— Kate Jackson, editor
e-News Exclusive
A Dietary Approach to the Management of Psoriasis

New research investigating for the first time the effects of modified intermittent fasting (MIF) on the skin of people with psoriasis has yielded promising results. Preliminary study findings presented at the European Academy of Dermatology and Venereology (EADV) Spring Symposium 2021 show a significant reduction in scaling and thickness in patients with mild psoriasis after following a MIF 5:2 diet (eating normally for five days and restricting calorie intake on two nonconsecutive days).

Psoriasis is a chronic, systemic immune-mediated inflammatory disease that causes raised plaques and scales on the skin’s surface. The disease affects between 2% to 3% of the world’s adult population, and <1% of children. Until now, the effect of dietary interventions on psoriasis severity has rarely been investigated, and although it is known that there is a link between obesity and psoriasis severity, the mechanism of action of this link is still unclear. This study sought to provide mechanistic evidence to inform whether there is a link between gut health and psoriatic lesions, as well as uncover any benefits of MIF in psoriasis management.

“We had observed positive results in mice with gut inflammation and psoriasis, with inflammation in the gut driving cutaneous symptoms,” shares Lynda Grine, PhD, a postdoctoral researcher in the department of dermatology at Ghent University in Belgium. “Through scientific curiosity and my own experience with fasting as a Muslim, I wanted to find out whether dietary intervention would have the same effects on human patients with psoriasis.”

Full story »
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